Signal Transduction Reagents and Kits
Echelon Biosciences Research Labs PI(5)P DIC8 AMMONIUM SALT 1 mg
Phosphatidylinositol 5-phosphate diC8 (PI(5)P diC8) is a synthetic, purified dioctanoyl PI(5)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. This item is non returnable
Echelon Biosciences Research Labs PI(5)P DIC8 AMMONIUM SALT 100 ug
Phosphatidylinositol 5-phosphate diC8 (PI(5)P diC8) is a synthetic, purified dioctanoyl PI(5)P.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. This item is non returnable
Enzo Life Sciences SB-216763 (5mg). CAS: 280744-09-4
Potent and selective inhibitor of GSK-3β (IC50=34nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke. Reduces pulmonary inflammation and fibrosis in a mouse model. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (>25mg/ml). Long Term Storage: Ambient.
Enzo Life Sciences L-JNKi1 (1mg)
This L-stereoisomer is a cell permeable JNK (c-Jun N-terminal kinase) inhibitor. For increased cell permeability the peptide was covalently linked to the 10 aa recognized by the TAT transporter. Neuroprotective agent for stroke. Inhibits the interaction between JNK (JNK-1, -2 and –3) and its substrate with the same IC50 (in vitro IC50 ~ 1µM), but is degraded more readily than the D-stereoisomer, thus requiring higher treatment concentrations in vitro and in vivo. Alternative name: JNK inhibitor 1 (L-stereoisomer), c Jun N terminal kinase peptide inhibitor 1, L stereoisomer. Purity: ≥95% (HPLC). Formulation: Lyophilized. Solubility: Soluble in water. Long Term Storage: -20°C.
MilliporeSigma BIOLOGY CHEMISCREEN153 MEMB
Life Sciences,Apoptosis & Cell Biology,CHEMISCREEN™ MEMBRANE PREPARATION RECOMBINANT HUMAN u (Mu) OPIOID RECEPTOR
Cell Signaling Technology SignalSlide Phospho-p44/42 MAPK (Thr202/Tyr204) IHC Controls 1 Pack
SignalSlide Phospho-p44/42 MAPK (Thr202/Tyr204) IHC Controls 1 Pack
Sigma Aldrich Fine Chemicals Biosciences Calpeptin >=98% (HPLC) | 117591-20-5 | MFCD00155623 | 25MG
Calpeptin >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 362.46 | 117591-20-5 | MFCD00155623 | 25MG
Aat Bioquest Calbryte™ 520 AM | 2x50ug
The intracellular calcium flux assay is a widely used method in monitoring signal transduction pathways and high throughput screening of G protein"coupled receptors (GPCRs) and calcium channel targets. Followed by Fluo-3 being introduced in 1989, Fluo-4, Fluo-8 and Cal-520 were later developed with improved signal/background ratio, and became the widely used Ca2+ indicators for confocal microscopy, flow cytometry and high throughput screening applications. However, there are still a few severe problems with Fluo-4. For example, as for Fluo-3, in all most all the intracellular calcium assays with Fluo-4 AM, probenecid is required to prevent the cell-loaded Fluo-4 from leaking out of cells. The use of probenecid with Fluo-4-based calcium assays compromises the assay results since probenecid is well-documented to have a variety of complicated cellular effects. Calbryte™ 520, AM is a novel fluorescent and cell-permeable indicator for the measurement of intracellular calcium.
Creative Biomart Human F7/Coagulation factor VII human
The product is human serine protease type enzyme that is involved in the extrinsic coagulation cascade which results in blood clotting.
Cell Biolabs Inc ViraDuctin™ AAV Transduction Kit, 10 transductions
AAV can infect both dividing and non-dividing cells and can be maintained in the human host cell, creating the potential for genome integration. Because AAV is a naturally defective virus, requiring provision of several factors in trans for productive infection, it is considered the safest viral vector to use. The AAV transduction process includes viral binding and entry, intracellular trafficking, nuclear transport, and viral second strand DNA synthesis. The viral second strand DNA synthesis has been shown to be the rate limiting step, which leads to inefficient transduction by AAV vectors. ViraDuctin™ AAV Transduction Kit is a proprietary formulation designed to increase the transduction efficiency of AAV vectors in a variety of cell types. This kit provides the following advantages: (1) Higher transduction efficiency in many cell types, (2) Easy to use, and (3) It is ideal for transduction of nonpermissive cells such as primary cells and stem cells. 10 transductions/kit.
Enzo Life Sciences PROTEOSTAT Thioredoxin-1 assay kit (2x96wells)
Applications: Fluorescent detection. Contents: PROTEOSTAT PDI detection reagent: 20 μL. Thioredoxin-1 (human) (recombinant): 2 vials x 80 μL. Insulin: 2 vials x 1.8 μmol. Aurothiomalate (inhibitor): 2 vials x 25 nmol. PBE buffer: 25 mL. Stop reagent: 1 mL. DTT: 2 vials x 1.3 mL. Deionized water: 5 mL
MilliporeSigma BIOLOGY CHEMISCREEN153 MEMB
Life Sciences,Apoptosis & Cell Biology,ChemiScreen Membrane Preparation Human Recombinant M1 Muscarinic Acetylcholine Receptor